Abstract
Background: Dementia is on the rise globally due to increasing life expectancies and population growth. Digital technologies may help detect early signs, enabling timely interventions to slow or reverse cognitive decline. However, to support the successful implementation of these digital technologies into health care settings, they must be acceptable to target users. Older adults and those with mild cognitive impairment (MCI) are at risk of developing dementia in later life and need to be able to use these technologies in order for this intervention to be approved and implemented in clinical practice.
Objective: This study explored the perspectives of older adults and those living with a clinical diagnosis of MCI on the acceptability of using various digital technologies that have the potential to support early dementia detection.
Methods: Participants were recruited from Boston University’s Alzheimer’s Disease Research Center. Participants selected at least 2 technologies from 9 different wearables and software to use for 2 weeks, at 3-month intervals, over a total duration of 2 years. A subgroup of self-selecting participants was interviewed after the first 2 weeks of use to gather initial perspectives regarding the acceptability of using the digital technologies. An inductive framework thematic analysis approach was used, assisted by NVivo (version 14.23.2; QSR International).
Results: In total, 13 individuals living with a clinical diagnosis of MCI and 11 adults aged 65 years and older were interviewed. Our analysis identified five key themes: (1) gamification, (2) wearability, (3) user guidance, (4) burden of use, and (5) usefulness. Gamified apps were generally liked, although users with little experience of digital games needed time to adjust. Wearables resembling everyday accessories (eg, watches) were preferred, but complaints about tight or uncomfortable straps were frequently reported. Clear instructions were critical to support correct use, but many participants would have liked more troubleshooting support when technical issues arose. The use of 5 or more devices led to a high burden, especially when devices had practicality issues such as not being waterproof. Devices offering personal feedback were perceived as useful to satisfy personal interests, though some questioned their usefulness within health care. Participants raised concerns about losing valued personal interactions with health care professionals and questioned how their existing health conditions and treatment for such conditions may affect the validity of the data collected by the devices.
Conclusions: These findings can guide researchers in choosing appropriate devices and minimizing burden. Future work should explore the views of those experiencing digital exclusion to ensure equitable access to dementia-detection technologies.
doi:10.2196/84004
Keywords
Introduction
Over 57 million people lived with dementia in 2021 []. The number of new cases has been estimated to increase by nearly 10 million annually []. The most common dementia-causing disease is Alzheimer disease, contributing to 60%‐70% of cases []. Neuropathological features of dementia-causing diseases start to occur up to 2 decades before the appearance of symptoms that are clinically detectable using current diagnostic techniques []. These diagnostic techniques often include a combination of pen-and-paper cognitive assessments to evaluate cognitive function, such as the Montreal Cognitive Assessment [], neuroimaging techniques to detect potential structural changes associated with dementia, and health care professionals’ judgment [,]. Researchers have explored the potential of cerebrospinal fluid or positron emission tomography imaging to detect biomarkers associated with the early signs of dementia-causing diseases []. However, these methods are invasive to patients and are not feasible to implement on a wide scale due to the considerable burden on health care resources (eg, financial cost, staff training or time, and scanning facilities) [-].
Over recent years, there has been significant interest in the use of digital technologies to support the early detection of dementia-causing diseases in a cost-effective, less invasive manner []. Digital technologies, such as wearable devices and software, have the potential to facilitate remote monitoring of individuals’ cognitive abilities and function [,]. These different technologies can be used for Alzheimer disease and related dementia assessment, covering diverse populations such as Lewy body, vascular dementias, frontotemporal dementias, and all severities of Alzheimer disease []. The successful implementation of such technologies into health care has been suggested to rely heavily on end users’ acceptance of using these digital technologies []. International public health agencies, such as the European Medicines Agency, the US Food and Drug Administration, and the National Institute for Health and Care Excellence, also require evidence of user involvement in the design and development of digital technology to ensure that patients understand how to use the digital technology and accept the design before the technology can be approved and implemented into clinical practice [-]. Those at risk of developing dementia later in life are likely to be the end users of such technologies. This includes older adults (aged 65 years and older) and those living with a clinical diagnosis of mild cognitive impairment (MCI) [,]. MCI is characterized by noticeable changes in memory or other cognitive abilities, such as the loss of language skills or visual or spatial perception, that are greater than what is expected with normal aging but not severe enough to interfere with daily life []. Although not everyone with a diagnosis of MCI progresses to dementia [], those with an MCI diagnosis have a 5-fold increased risk of developing dementia later in life []. Therefore, to help identify acceptable digital technologies that could potentially support the early detection of dementia-causing diseases, we conducted a qualitative study to explore the perspectives of older adults and those living with MCI on the acceptability of using a range of different digital technologies.
Methods
Study Design
This study was part of the Early Detection of Neurodegenerative Diseases (EDoN) initiative, which aimed to develop a “digital toolkit” that contained technologies with the potential to detect early signs of dementia-causing diseases []. To support the development of the EDoN digital toolkit, we conducted semistructured interviews with potential end users (older adults and those living with MCI) to explore factors affecting concurrent acceptability (the extent to which an individual receiving an intervention finds it appropriate while participating []) of different digital technologies.
Participant Recruitment and Eligibility
Participants were recruited through an EDoN-affiliated research cohort at Boston University-Alzheimer’s Disease Research Centre (BU-ADRC). The BU-ADRC is a National Institute of Health–funded center that provides resources to support Alzheimer disease research, including a network of individuals without cognitive decline, MCI, and dementia, all older than 50 years of age and willing to take part in research []. Individuals were eligible to take part if they owned a smartphone, had access to the internet at home, and were fluent in the English language.
Procedure
Participants were informed of the 9 different commercially available digital technologies to choose from, what the technologies did (ie, modalities they measured), and how to use them. Participants then chose a minimum of 2 technologies to use over the course of 3 months (). These digital technologies were selected by EDoN and BU-ADRC for the study, as they each measure different modalities associated with the early signs of dementia-causing diseases and thus have the potential to support early detection. These technologies included 3 gamified active smartphone apps (ie, involve an element of gameplay, such as following to achieve a goal), 2 passive apps (smartphone and computer), and 4 wearable technologies (2 wrist-worn activity monitors, a smart ring, and an electroencephalogram headband; the modalities each digital technology measured are presented in ). A member of the research team (ZP and SR), who had received training on how to set up and use the technologies by the technology companies and developers, provided each participant with their selected digital technologies and supported the initial onboarding process during an in-person visit. The onboarding process involved activities such as helping participants download the relevant apps, create accounts, and pair the wearable devices with their personal smartphones. They also provided written instructions on how to use the digital technologies that participants took home and answered any questions about the technologies.
| Technology type | Method of assessment | Metrics evaluated | Frequency of data collection | Level of engagement required from participants |
| Active smartphone app 1 |
|
|
| 30‐35 minutes using the app |
| Active smartphone app 2 |
|
|
| 10‐15 minutes using the app |
| Active smartphone app 3 |
|
|
| 10‐15 minutes of using the app |
| Passive smartphone app |
|
|
| Data collected passively for 2 weeks without user input |
| Passive computer software |
|
|
| Data collected passively for 2 weeks without user input |
| Wrist-worn activity monitor 1 (can be alternated with the other wrist-worn activity monitor if the participant opted to use both devices) |
|
|
| Wear for the duration of the 2-week study period (including overnight) |
| Wrist-worn activity monitor 2 (can be alternated with the other wrist-worn activity monitor if the participant opted to use both devices) |
|
|
| Wear for the duration of the 2-week study period (including overnight) |
| Headband |
|
|
| Wear overnight for a minimum of 3 consecutive nights, ideally a full 2 weeks |
| Ring (worn on the thumb or index finger) |
|
|
| Wear overnight for a minimum of 2 consecutive nights, ideally a full 2 weeks |
Data Collection
Participants completed a quantitative demographic questionnaire to gather relevant data on their sociodemographic background (eg, date of birth and biological sex [assigned at birth]) and medical history (eg, self-reported clinical diagnosis of MCI). Researchers (ZP or SR) shared information about this qualitative study with all participants. Researchers used the information provided in the questionnaire to monitor diversity across interested individuals to ensure that our sample consisted of both those living with a clinical diagnosis of MCI and those without any clinically diagnosed cognitive decline. A subgroup of self-selecting participants were invited to a remote (Zoom Technologies, Inc, or by telephone) semistructured interview after their first 2 weeks of using the digital technologies, occurring between April 2022 and June 2023. Interviews were conducted by a member of the research team (ZP or SR) who was trained by an experienced qualitative researcher (SW). All interviews were audio-recorded using the videoconference software or a dictaphone. A flexible interview topic guide (), which was extensively piloted with 7 individuals with varying degrees of cognitive impairment and 2 caregivers, was used to guide and structure the discussions []. The topic guide was designed to gather participants’ perspectives on the different digital technologies they had selected to use.
Data Analysis
Audio recordings of the interviews were transcribed verbatim by a transcription company (Datagain) and checked for accuracy by the research team (RK). Transcripts were uploaded to NVivo (version 14.23.2; QSR International) to assist our inductive thematic framework approach, a form of codebook thematic analysis [,]. Inductive thematic analysis is the process of identifying recurring concepts to create themes without using any preconceptions or preexisting framework []. This allowed us to focus on the views, perspectives, and experiences of participants without being influenced by any preexisting theories, ensuring that our analysis is an accurate reflection of the data []. The framework approach involved following 5 stages, beginning with members of the research team (SW and EB) familiarizing themselves with the data by reading and rereading the transcripts, before generating initial codes [,]. Core concepts (a central concept that holds associated shared meaning patterns, ie, themes) were then formed by grouping codes to create an analytical framework, which was applied across the whole dataset. A framework matrix was used to chart the data, consisting of rows (cases), columns (codes), and “cells” of data to help summarize the large quantity of data collected. This framework approach allowed multiple coders (SW and EB) to analyze the data and enabled our multidisciplinary team, with professional backgrounds in neuroscience, pharmacy, population health sciences, digital health inequities, physiology, and psychology, to review the analysis and interpret the data to provide a richer understanding of participants’ views and experiences [,]. The rigidity of the framework approach also allowed us to explore specific project aims (to explore the perspectives of potential end users on the acceptability of using a range of digital technologies) [,]. The constant comparative method, involving the researchers (SW and EB) moving backward and forward between the data, comparing data, and evolving explanations, was used to further develop key themes []. Regular meetings with authors (SW, EB, SPS, ZP, SR, and CT) were held throughout the analysis to ensure that the themes were accurately reflected by the data and that data saturation (the stage where repetitive codes or themes are identified, and no new information or relationships between them emerge in new transcripts) [] was reached before participant recruitment stopped. Several factors were considered to identify when thematic data saturation was achieved, such as the quality of the interviews (eg, length and depth of detail captured), number of interviews, and lack of occurrence of new information in interviews conducted after thematic data saturation was thought to be achieved [-].
Researcher Characteristics
The interviewers (ZP and SR) were male research assistants at Boston University School of Medicine at the time of this study and did not disclose their background to participants. There were no prior relationships between the participants and the research team. The interviewers were trained by a member of the team (SW) who had a master’s in cognitive neuroscience and experience in interviewing older adults and those living with cognitive decline (eg, MCI and dementia). The researchers involved in the analysis (SW, EB, CT, and SPS) were experienced qualitative researchers at various career stages, with diverse academic backgrounds in pharmacy, neuroscience, and public health. This multidisciplinary approach ensured a comprehensive understanding of participants’ experiences and mitigated bias from each researcher’s interests.
Rigor and Trustworthiness
Various strategies were used to ensure that rigor was upheld during this qualitative research. This included following the SRQR (Standards for Reporting Qualitative Research) [], completing the COREQ (Consolidated Criteria for Reporting Qualitative Research) checklist () [], and ensuring trustworthiness by following guidance outlined by Nowell et al [] to achieve credibility, transferability, dependability, and confirmability of the study. To address credibility, we piloted the topic guide to ensure that the questions could be easily understood by participants. Transferability was achieved by providing a detailed description of the methods, allowing those who sought to transfer the findings to their own research or settings to judge it on a case-by-case basis. To achieve dependability, we used audit trails to clearly document logical decisions so others can understand how and why decisions were made. According to Lincoln and Guba [], confirmability is established when credibility, transferability, and dependability are achieved.
Ethical Considerations
This study was approved by the institutional review board at Boston University Medical Center (IRB: H-40542). This study was conducted in accordance with the principles of the Declaration of Helsinki (2024). Written and verbal informed consent to participate in the study was obtained from all participants. Participants were not remunerated after taking part in the study. Written informed consent to publish the findings was obtained from relevant participants. Participants were fully informed of the anonymization process (eg, names were replaced with an identification number).
Results
Participant Characteristics
In total, 24 individuals participated in this qualitative study, of which 13 had a clinical diagnosis of MCI, and 11 had no cognitive impairment but were aged 65 years and older. Half were female (n=12), and the average age of the sample was 72 years (). The specific type and number of technologies used by each participant over the first 2-week period are shown in . Semistructured interviews lasted between 25 and 45 minutes.
| ID | Sex | Diagnosis | Digital technology used | Total number of technologies over the first 2-week period | ||||||||
| Apps | Wearables | |||||||||||
| Active app 1 | Active app 2 | Active app 3 | Passive smartphone app | Passive computer software | Wrist-worn activity monitor 1 | Wrist-worn activity monitor 2 | Headband | Ring | ||||
| P1 | Female | No cognitive impairment | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 7 | ||
| P2 | Male | MCI | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 8 | |
| P3 | Male | No cognitive impairment | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 6 | |||
| P4 | Female | No cognitive impairment | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 6 | |||
| P5 | Female | No cognitive impairment | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 8 | |
| P6 | Female | MCI | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 7 | ||
| P7 | Male | No cognitive impairment | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 7 | ||
| P8 | Female | No cognitive impairment | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 8 | |
| P9 | Male | No cognitive impairment | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 9 |
| P10 | Female | No cognitive impairment | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 6 | |||
| P11 | Female | No cognitive impairment | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 7 | ||
| P12 | Male | No cognitive impairment | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 8 | |
| P13 | Male | MCI | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 8 | |
| P14 | Male | MCI | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 7 | ||
| P15 | Male | MCI | ✓ | ✓ | ✓ | ✓ | ✓ | 5 | ||||
| P16 | Male | MCI | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 7 | ||
| P17 | Female | MCI | ✓ | ✓ | 2 | |||||||
| P18 | Female | MCI | ✓ | ✓ | ✓ | ✓ | 4 | |||||
| P19 | Female | MCI | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 6 | |||
| P20 | Male | MCI | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 8 | |
| P21 | Female | No cognitive impairment | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 7 | ||
| P22 | Male | MCI | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 7 | ||
| P23 | Female | MCI | ✓ | ✓ | ✓ | ✓ | ✓ | 5 | ||||
| P24 | Male | MCI | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 8 | |
aMCI: mild cognitive impairment.
Our data analysis generated 5 key themes, which describe factors affecting the concurrent acceptability of a range of different digital technologies. These themes include (1) gamification, (2) wearability, (3) user guidance, (4) burden of use, and (5) usefulness (). Each theme is described in detail below using direct anonymized quotes from participants; these appear in quotation markers (“”). To improve the flow and clarity, the author has added additional information to some quotes, indicated by square parentheses ([]), and removed some words, indicated by an ellipse in square parentheses ([…]). To ensure confidentiality, participant names have been replaced with their participant ID, which was assigned in chronological order, alongside additional relevant information to provide further context (eg, Participant 1, no cognitive impairment, used 7 technologies=participant who was interviewed first, did not have any diagnosed cognitive impairment, and used 7 of the 9 digital technologies available in this study). We take each of these themes in turn below.

Gamification
Many participants living with MCI enjoyed the challenge of games within the active apps and felt that they were “keeping their brain alive” (Participant 23, living with MCI, used 5 technologies). Some participants without cognitive impairment who described themselves as competitive “wanted to get an A-Plus all the time” (Participant 8, no cognitive impairment, used 8 technologies). This participant described developing strategies in an attempt to improve their performance, such as verbalizing which direction they needed to swipe in the swiping task: “I think I did quite a bit better when I realized that saying it [the direction] out loud reinforced it” (Participant 8, no cognitive impairment, used 8 technologies). There was also a strong preference among those without cognitive impairment to select the active apps, which had “a little bit more variety” (Participant 7, no cognitive impairment, used 7 technologies) in the gamified tasks. This helped participants avoid the games becoming repetitive and boring. However, some older adults without cognitive impairment who had “never played video games” (Participant 4, no cognitive impairment, used 6 technologies) before felt that their lack of experience may have impacted their ability to complete the gamified task, as it took longer to understand the requirements: “I don’t play video games. So, it took me a while [to understand what to do]” (Participant 21, no cognitive impairment, used 7 technologies). When participants did not perform as well as they would have liked on the gamified tasks, they described feeling anxious at the thought of having to play the game again, reducing their motivation to use the app again.
Wearability
Independent of cognitive decline, participants found the smart ring “easy [to use and] no big deal [to wear]” (Participant 11, no cognitive impairment, used 7 technologies). Similarly, most participants found the wrist-worn activity monitors acceptable because they were “just like wearing a watch, you know I don’t even know it’s there, except for the buzzes. So that’s fine” (Participant 4, no cognitive impairment, used 6 technologies). However, those who did not usually wear a watch discussed feeling the need to get “back in that habit” (Participant 1, no cognitive impairment, used 7 technologies), as they were “just not used to it” (Participant 9, no cognitive impairment, used 9 technologies). Many participants expressed hesitation around putting on the headband, as “it’s not the normal thing that I would like to be doing to go to sleep” (Participant 9, no cognitive impairment, used 9 technologies). Those who had used a medical wearable device on their head prior to this study were particularly concerned about the comfort of wearing it:
I had tried a sleep apnoea mask before, and I couldn’t do that [sleep with the mask on], and I didn’t like it. I thought this [the headband] was going to be similar.
[Participant 22, living with MCI, used 7 technologies]
In terms of comfort, some participants did not like the plastic straps on the wrist-worn activity monitor because “occasionally it got a little bit uncomfortable and sweaty, and if it’s too tight, it’s hard to move on my wrist” (Participant 5, no cognitive impairment, used 8 technologies). The headband also had some issues, as the electroencephalogram sensor prongs were felt to be “digging into the back of my head” (Participant 12, no cognitive impairment, used 8 technologies), causing discomfort and waking up participants during the night. This discomfort may have been linked to how tight the headband straps were adjusted, as one participant described how “the first night was terrible, but then I loosened [the straps], I used the extenders, so it wasn’t so tight and then it wasn’t quite so bad” (Participant 4, no cognitive impairment, used 6 technologies).
User Guidance
All participants felt that the user guides provided by the research team were “very helpful” (Participant 1, no cognitive impairment, used 7 devices) and “easy to follow” (Participant 3, no cognitive impairment, used 6 technologies). However, the guidance given within the active and passive apps as well as the apps associated with the wearable technologies (used to collect data) required further improvement to support those with MCI. One participant described having “trouble with the [headband] around my [her] head because the directions were not clear enough” (Participant 19, living with MCI, used 6 technologies). In this case, the participant had worn the headband the wrong way around, and the data were not recorded over multiple nights. Others explained how it was not obvious “when it [wrist-worn device] needed to be charged” (Participant 8, no cognitive impairment, used 8 technologies) and would like more guidance on this.
A key area omitted in the user guides was how to troubleshoot technical issues. One of the most frequently reported technical issues involved difficulty syncing the headband and its associated app. Some participants described receiving “a pop up on the app that said [...], now that you’ve paired, the headband will recognize the device, but it never did” (Participant 5, no cognitive impairment, used 8 technologies). Another participant recalled how the smartphone app often froze, resulting in him having to “hit the [app home] button again” (Participant 14, living with MCI, used 7 technologies) to close the app, reopen it, and repeat the games. He described feeling frustrated at being unable to complete the required task in one go and questioned whether he was “doing something [wrong like] touching that is causing this or is it something in the game itself that is too sensitive?” (Participant 14, living with MCI, used 7 technologies). Experiencing such technical issues without any guidance on how to overcome them left some participants feeling “helplessness when it [the technology] doesn’t work” (Participant 24, living with MCI, used 8 technologies).
Burden of Use
Participants with and without MCI described the burden of using 5 or more technologies, explaining how it was “a little invasive in terms of my time” (Participant 9, no cognitive impairment, used 9 technologies) and how they would have liked a shorter schedule of assessments so that it “would not wear me down” (Participant 21, no cognitive impairment, used 7 technologies). The burden of using the devices was particularly evident among participants who had “a lot going on in your [their] life” (Participant 6, living with MCI, used 7 technologies) or were on holiday during the 2-week period. One participant explained how they did not use the devices during their holiday as they “didn’t really want to have to do a lot of setting [up of the technology]” (Participant 11, no cognitive impairment, used 7 technologies). Some participants developed strategies to help “settle into some kind of pattern that was reasonable” (Participant 1, no cognitive impairment, used 7 technologies), with one participant making “a little chart of how many days I had to do this, that, and the next thing” (Participant 11, no cognitive impairment, used 7 technologies). This helped integrate the technology into their everyday lives.
Once a routine had been established, participants without cognitive impairment reflected on the practicality of using the devices. Some female participants were self-conscious of how the wearable devices looked on them, with one participant explaining how “if I’m going to wear anything on my wrist, if I wanted to, [it] would be a pretty bracelet” (Participant 11, no cognitive impairment, used 7 technologies). Other participants, who liked water sports, described the wrist-worn activity monitors as "a bit of a hassle [...] I was out in the swimming pool every day because I had to take the [monitors] off” (Participant 12, no cognitive impairment, used 8 technologies). As the devices were only water-resistant, not waterproof, some participants worried that they may have accidentally damaged the devices when they exposed them to water. One participant recounted how they
hopped into the shower with it. And I immediately hopped out and wiped it, and everything. It was fine. But I was a little bit, “Oh God, what have I done now?”
[Participant 11, no cognitive impairment, used 7 technologies]
Usefulness
Participants found the digital technologies useful, particularly devices that allowed their scores on the gamified tasks to be compared over different days. Others living with a clinical diagnosis of MCI found that the health-related metrics (eg, heart rate) measured by the wrist-worn activity monitor were particularly useful. However, some participants living with MCI would have liked to interpret the feedback from the devices in further detail, particularly the sleep metrics: “I love looking at the feedback [sleep data from the headband] and, I wish I knew more about that so that was interesting” (Participant 6, living with MCI, used 7 technologies). Another participant without cognitive impairment felt that it would be useful to compare his metrics with others of a similar age:
It would be nice to be able to know that against this group of people [of similar age], you’re doing good, [or] you’re not doing good. So, if you need to change something [to improve your health and wellbeing], you could change it.
[Participant 7, no cognitive impairment, 7 technologies]
Most participants were hopeful that these digital technologies might be able to send reports directly to their health care provider. Others were more cautious and stated that they would “hate to see everything done high tech. I don’t want to lose the personal interaction between physicians and health care people and patients” (Participant 10, no cognitive impairment, used 6 technologies). Participants with existing health conditions worried about whether these conditions might impact the validity of the data collected by the digital technologies, with one explaining how she had a recent fall and “I think that they didn’t expect me to live, obviously I’ve done very well [with their health after the fall], but yes, I don’t think I’m as sharp [cognitively]” (Participant 10, no cognitive impairment, used 6 technologies). Some also questioned whether the data collected might be affected by treatment for a particular condition. For example, one participant who wore a sleep apnea mask at night queried how the oximeter sensor in the ring would “take into consideration that I’ve got oxygen on at night?” (Participant 10, no cognitive impairment, used 6 technologies).
Discussion
Principal Findings
This qualitative study explored the views of individuals potentially at risk of developing dementia, specifically older adults and those living with a clinical diagnosis of MCI, on the acceptability of using a range of different digital technologies. A range of 9 diverse technologies were used, and novel insights gained into the burden of using multiple devices and the key factors influencing acceptability. Most participants liked the gamified tasks in active apps, though some participants who were less familiar with digital games needed more time to adjust. Wearables placed on the body in areas of everyday accessories (eg, watches and rings) were preferred, but the straps used to fix the wearable to the body were sometimes found to be uncomfortable, particularly when worn too tightly. Clear, concise user instructions and troubleshooting guidance were found to be essential to ensure the proper use of the digital technologies, and further improvements were highlighted. Devices providing personally relevant feedback (eg, test scores or health metrics) were also well-received, although many questioned their usefulness within health care.
Gamification has great potential to increase participant engagement in cognitive tasks []. Findings from this study strongly support this stance, as gamification of cognitive testing through active smartphone apps was generally accepted by participants as challenging but also an engaging experience. Furthermore, a study conducted by Ríos Rincón et al [] found that older adults preferred smartphone cognitive games compared to paper-based cognitive activities, and they experienced higher levels of engagement and positive cognitive effects while playing the smartphone games compared to paper-based activities. However, there are a number of considerations when using gamification in this manner. First, it is important to find the right balance between challenging the user with games, but also the goals within the games being achievable. Previous research has highlighted how if a digital game is too hard, users are more likely to experience low self-esteem, annoyance, and a sense of insecurity []. Second, an individual’s digital literacy skills, ability to use a hand-held digital device, and digital self-efficacy must be considered to avoid contributing toward digital health inequities once the technology is implemented into health care. This aspect is particularly important because individuals in this study were eligible to participate if they had owned a smartphone and had access to the internet at home. Some older adults have little to no experience of using games on a digital device, which they perceived had negatively impacted their ability to complete the task. The wider literature also suggests that older adults (aged 65 years and older) and those living with MCI are at risk of experiencing digital exclusion [,].
Where the device was worn on the body and the comfort of wearing the technology were 2 key elements found to affect the acceptability of a wearable device. Wrist-worn activity monitors and the smart ring were found to be more acceptable than the headband, which was consistent with previous findings [-]. This may be due to the increased familiarity and understanding of smartwatches [,] and the social acceptability of wearing the device on your wrist and using your hands to make gestures and touches to the device []. Comfort of the wearable devices when worn correctly versus incorrectly (eg, too tight) was also found in this study to impact acceptance, which is echoed in the wider literature [,]. This highlights the importance of providing adequate and clear user instructions on how to wear and use the digital technologies.
User instructions must also contain guidance on how to overcome technical issues, such as how issues with syncing a wearable device to its associated smartphone app and what to do if an active smartphone app freezes. These instructions need to be written in such a way that they are suitable for those with cognitive impairment. Experiencing technical issues without any guidance on how to overcome them led to some participants in this study feeling hopeless. Law et al [] found that professional caregivers of those with cognitive decline (health care professionals and staff at a retirement facility) were concerned that technical issues with digital technologies would cause confusion among those with cognitive impairments and would likely prevent them from engaging with the technology if the issues could not be fixed. Therefore, technical support must be given to end users and caregivers of those with cognitive impairment to promote acceptance, use, and engagement with the devices.
The burden placed on end users when using multiple devices was another key area that emerged in this study. Those who used 5 or more different digital technologies felt a high level of burden, and some found it challenging to integrate these devices into their busy daily lives. However, using digital technologies to support the early detection of dementia-causing diseases is viewed as a less invasive approach, but we found that the greater the number of devices that a participant used, the more it can potentially be invasive of their time. Furthermore, it brings into question if digital technology’s ability to offer remote data collection and potentially shorter assessment periods only displaced the burden from health care systems onto end users rather than reduced the burden overall []. To reduce end-user burden, this study suggests that users should not be asked to use more than 4 devices at any 1 time and that the devices are waterproof to reduce the number of times the device needs to be removed. The wider literature also suggests selecting digital technologies that are easy to use and/or wear and devices that need minimal interaction (eg, have a long battery life to reduce charging) to reduce the number of tasks required [,].
The ability of the devices to provide personal feedback, such as test scores and health-related metrics (eg, heart rate), was perceived as useful and interesting by participants in this study. Such a finding is echoed in the literature, which also suggests that feedback from digital health technologies drives engagement and continued use of technologies among older adults [,]. Previous studies have also found that feedback from activity monitors may motivate older adults to increase their physical activity []. Despite the benefits of digital technologies in satisfying personal interests, many participants also raised concerns about potentially losing valued personal interactions with health care professionals and whether their existing health conditions and treatment may affect the validity of the data collected. Similar concerns about losing human connection in health care interaction have been reported in the wider literature []; however, there has been little to no research at the time of this study, discussing users’ concerns about how their health conditions and medical treatments may affect the validity of the data. This novel insight must be further explored to understand to what extent health conditions and treatments are likely to impact the validity of the data collected and how to mitigate such concerns.
Strengths, Limitations, and Areas for Future Research
Multiple strategies were used in this study to ensure rigor and trustworthiness, such as collecting data until thematic data saturation was achieved and piloting the topic guide [,]. The inductive nature of our analysis supported the identification of novel insights, such as the burden of using multiple devices and concerns regarding the impact of existing health conditions on specific metrics. Furthermore, the range of different technologies used in the study provides originality and contributes to our understanding of accessibility and usability of technologies for health care purposes. A key limitation of this study is that individuals self-selected to participate in the study and were required to own a smartphone and have access to internet connectivity at home. There were no strategies put in place to support the recruitment of those who may have experienced or are experiencing digital exclusion, such as those of low socioeconomic status who cannot afford a smartphone, or those who live in rural areas who may not have access to a reliable internet connection at home []. Some insights into those with little to no experience of using digital technologies (eg, games on a smartphone via an app) were gathered in this study, but further research is needed to gain a deeper understanding of the unique views, perceptions, and opinions of those experiencing digital exclusion and to ensure that the digital intervention does not contribute to digital health inequalities when implemented in practice. Although our study provides a rich in-depth understanding regarding acceptability, usability, and user burden, the inclusion of a quantitative measure of acceptability, usability, and/or burden, such as System Usability Scale [], could have facilitated data triangulation and potential comparisons to be made between technologies and subgroups (MCI vs no impairment or high vs low device count).
Conclusions
This novel qualitative study highlighted factors affecting concurrent acceptability of using a range of digital technologies that have the potential to support early dementia detection from the perspectives of potential end users. This information will help contribute to researchers’ decision-making regarding how many devices the participants should be asked to use and the key elements (eg, comfort, place a device is worn, and waterproof) of a digital device that must be considered to improve acceptance and engagement. Future research is needed to gain a deeper understanding of the factors that affect the acceptance of using digital technologies to support early dementia detection among those experiencing digital exclusion, as our recruitment design could be viewed as limiting inclusion of this population, and their views are necessary to ensure that digital health equity can be supported.
Acknowledgments
The authors would like to thank all participants for their time and contribution to our research. Generative artificial intelligence was not used in any portion of the manuscript generation.
Funding
This work has been supported by the Early Detection of Neurodegenerative Diseases research initiative, funded by Alzheimer’s Research UK with support from Gates Ventures and the Alzheimer’s Drug Discovery Foundation through its Diagnostic Accelerator Project. This project also received funding from the American Heart Association. SPS and CT were funded by the National Institute of Health and Care Research (NIHR205190). The views expressed are those of the authors and not necessarily those of the NIHR or the Department of Health and Social Care. The funder of the study had no role in study design, data collection, data analysis, data interpretation, or writing of the report.
Data Availability
The datasets generated and analyzed during this study are not publicly available due to a potential breach of participant confidentiality. Anonymized datasets may be available from the corresponding author upon reasonable request.
Authors' Contributions
SW (lead author) provided qualitative methodology training to the coauthors responsible for data acquisition (ZP and SR), obtained ethics approval, conducted data analysis and interpretation, created visualizations, and drafted, revised, and completed the current version of the manuscript. SW also took responsibility for ensuring that any questions related to the accuracy or integrity of the qualitative work were appropriately investigated and resolved. EB contributed to data analysis and interpretation and provided feedback during the drafting and revision of the manuscript. ZP contributed to data acquisition, obtained ethics approval, supported data interpretation, recruited participants, managed the participant onboarding process, and provided technical support. SR contributed to data acquisition, supported data interpretation, recruited participants, managed the participant onboarding process, and provided technical support. SB and TW contributed to project management. SL supervised ZP and SR and contributed to obtaining ethics approval. RK quality-checked the interview transcripts. CT supervised the lead author (SW), contributed to data analysis and interpretation, and provided feedback on drafts. ZW and RA contributed to funding acquisition. SPS (corresponding author) conceived the study, contributed to methodology development, acquired funding, supervised SW and EB, contributed to data analysis and interpretation, approved the final version of the manuscript, and provided feedback on drafts. SPS also took responsibility for ensuring that any questions related to the accuracy or integrity of the qualitative work were appropriately investigated and resolved.
Conflicts of Interest
None declared.
References
- Dementia: key facts. World Health Organization. 2025. URL: https://www.who.int/news-room/fact-sheets/detail/dementia [Accessed 2025-07-24]
- Beyer L, Stocker H, Rujescu D, et al. Amyloid‐beta misfolding and GFAP predict risk of clinical Alzheimer’s disease diagnosis within 17 years. Alzheimers Dement. Mar 2023;19(3):1020-1028. [CrossRef]
- Nasreddine ZS, Phillips NA, Bédirian V, et al. The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. J Am Geriatr Soc. Apr 2005;53(4):695-699. [CrossRef] [Medline]
- Tests for diagnosing dementia. NHS. 2023. URL: https://www.nhs.uk/conditions/dementia/diagnosis-tests/ [Accessed 2025-07-24]
- Dementia: diagnosis and tests. Mayo Clinic. 2025. URL: https://www.mayoclinic.org/diseases-conditions/dementia/diagnosis-treatment/drc-20352019 [Accessed 2025-07-24]
- Hameed S, Fuh JL, Senanarong V, et al. Role of fluid biomarkers and PET imaging in early diagnosis and its clinical implication in the management of Alzheimer’s disease. J Alzheimers Dis Rep. Feb 12, 2020;4(1):21-37. [CrossRef] [Medline]
- Anderson R, Knapp M, Wittenberg R, Handels R, Schott JM. Economic modelling of disease-modifying therapies in Alzheimer’s disease. Personal Social Services Research Unit, London School of Economics and Political Science; 2018. URL: https://www.lse.ac.uk/cpec/assets/documents/EconomicmodellingAD.pdf [Accessed 2026-05-22]
- Dementia attitudes monitor. Alzheimer’s Research UK; 2018. URL: https://www.dementiastatistics.org/wp-content/uploads/2019/02/Dementia-Attitudes-Monitor-Wave-1-Report.pdf#zoom=100 [Accessed 2025-07-24]
- Frey AL, Karran M, Jimenez RC. Harnessing the potential of digital technologies for the Early Detection of Neurodegenerative diseases (EDoN). Open Science Framework. 2019. URL: https://osf.io/preprints/osf/u49z5_v1 [Accessed 2026-05-22]
- Lawson L, Mc Ardle R, Wilson S, Beswick E, Karimi R, Slight SP. Digital endpoints for assessing instrumental activities of daily living in mild cognitive impairment: systematic review. J Med Internet Res. Jul 25, 2023;25:e45658. [CrossRef] [Medline]
- Lott SA, Streel E, Bachman SL, et al. Digital health technologies for Alzheimer’s disease and related dementias: initial results from a landscape analysis and community collaborative effort. J Prev Alzheimers Dis. 2024;11(5):1480-1489. [CrossRef] [Medline]
- Slattery P, Saeri AK, Bragge P. Research co-design in health: a rapid overview of reviews. Health Res Policy Syst. Feb 11, 2020;18(1):17. [CrossRef] [Medline]
- Madanian S, Nakarada-Kordic I, Reay S, Chetty TH. Patients’ perspectives on digital health tools. PEC Innov. Dec 2023;2:100171. [CrossRef] [Medline]
- Evidence standards framework for digital health technologies. National Institute for Health and Clinical Excellence; 2022. URL: https://www.nice.org.uk/corporate/ecd7 [Accessed 2025-07-24]
- Questions and answers: qualification of digital technology-based methodologies to support approval of medicinal products. European Medicines Agency. 2020. URL: https://www.ema.europa.eu/en/documents/other/questions-and-answers-qualification-digital-technology-based-methodologies-support-approval-medicinal-products_en.pdf [Accessed 2025-07-24]
- Digital health technologies for remote data acquisition in clinical investigations. US Food and Drug Administration. 2023. URL: https://www.fda.gov/regulatory-information/search-fda-guidance-documents/digital-health-technologies-remote-data-acquisition-clinical-investigations [Accessed 2025-07-24]
- Overview: Alzheimer’s disease. NHS. 2024. URL: https://www.nhs.uk/conditions/alzheimers-disease/#:~:text=Who%20is%20affected?,or%20young%2Donset%20Alzheimer’s%20disease [Accessed 2025-07-24]
- Campbell NL, Unverzagt F, LaMantia MA, Khan BA, Boustani MA. Risk factors for the progression of mild cognitive impairment to dementia. Clin Geriatr Med. Nov 2013;29(4):873-893. [CrossRef] [Medline]
- Albert MS, DeKosky ST, Dickson D, et al. The diagnosis of mild cognitive impairment due to Alzheimer’s disease: recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease. Alzheimers Dement. May 2011;7(3):270-279. [CrossRef] [Medline]
- Grill JD, Di L, Lu PH, et al. Estimating sample sizes for predementia Alzheimer’s trials based on the Alzheimer’s Disease Neuroimaging Initiative. Neurobiol Aging. Jan 2013;34(1):62-72. [CrossRef] [Medline]
- Sekhon M, Cartwright M, Francis JJ. Acceptability of healthcare interventions: an overview of reviews and development of a theoretical framework. BMC Health Serv Res. Jan 26, 2017;17(1):88. [CrossRef] [Medline]
- Common questions about participating in research. Boston University Alzheimer’s Disease Research Centre. 2025. URL: https://www.bu.edu/alzresearch/education-program/common-questions-about-participating-in-research/#:~:text=I%20am%20healthy.,Our%20Commitment%20to%20you [Accessed 2025-07-24]
- Wilson S, Ardle RM, Tolley C, Slight S. Usability and acceptability of wearable technology in the early detection of dementia. Alzheimers Dement. Dec 2022;18 Suppl 2:e059820. [CrossRef] [Medline]
- Ritchie J, Spencer L. Qualitative data analysis for applied policy research. In: Bryman A, Burgess RG, editors. Analyzing Qualitative Data. Routledge:1994. [CrossRef]
- Gale NK, Heath G, Cameron E, Rashid S, Redwood S. Using the framework method for the analysis of qualitative data in multi-disciplinary health research. BMC Med Res Methodol. Sep 18, 2013;13:117. [CrossRef] [Medline]
- Glaser BG. The constant comparative method of qualitative analysis. Soc Probl. Apr 1965;12(4):436-445. [CrossRef]
- Yang L, Qi L, Zhang B. Concepts and evaluation of saturation in qualitative research. Adv Psychol Sci. Mar 1, 2022;30(3):511-521. [CrossRef]
- Francis JJ, Johnston M, Robertson C, et al. What is an adequate sample size? Operationalising data saturation for theory-based interview studies. Psychol Health. Dec 2010;25(10):1229-1245. [CrossRef] [Medline]
- Marshall MN. Sampling for qualitative research. Fam Pract. Dec 1996;13(6):522-525. [CrossRef] [Medline]
- O’Brien BC, Harris IB, Beckman TJ, Reed DA, Cook DA. Standards for reporting qualitative research: a synthesis of recommendations. Acad Med. Sep 2014;89(9):1245-1251. [CrossRef] [Medline]
- Tong A, Sainsbury P, Craig J. Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups. Int J Qual Health Care. Dec 2007;19(6):349-357. [CrossRef] [Medline]
- Nowell LS, Norris JM, White DE, Moules NJ. Thematic analysis: striving to meet the trustworthiness criteria. Int J Qual Methods. 2017;16(1). [CrossRef]
- Lincoln YS, Guba EG. But is it rigorous? Trustworthiness and authenticity in naturalistic evaluation. New Direct Program Eval. Jun 1986;1986(30):73-84. [CrossRef]
- Khaleghi A, Aghaei Z, Mahdavi MA. A gamification framework for cognitive assessment and cognitive training: qualitative study. JMIR Serious Games. May 18, 2021;9(2):e21900. [CrossRef] [Medline]
- Ríos Rincón AM, Daum C, Miguel Cruz A, Liu L, Stroulia E. Feasibility and acceptability of a serious mobile-game intervention for older adults. Phys Occup Ther Geriatr. Jul 3, 2022;40(3):295-318. [CrossRef]
- Groenewoud H, Lange J, Schikhof Y, Astell A, Joddrell P, Goumans M. People with dementia playing casual games on a tablet. Gerontechnology. May 22, 2017;16(1):37-47. [CrossRef]
- Wilson S, Tolley C, McArdle R, Slight R, Slight S. Who is most at risk of digital exclusion within healthcare? Int J Pharm Pract. Apr 29, 2024;32(Suppl 1):i3-i4. [CrossRef]
- Liu X, Wang X, Zhang H, Pei M, Li N. Relationship between digital exclusion and cognitive impairment in Chinese adults. Front Aging Neurosci. 2023;15:1194348. [CrossRef] [Medline]
- Scherer MJ, Craddock G, Mackeogh T. The relationship of personal factors and subjective well-being to the use of assistive technology devices. Disabil Rehabil. 2011;33(10):811-817. [CrossRef] [Medline]
- Zeagler C. Where to wear it: functional, technical, and social considerations in on-body location for wearable technology 20 years of designing for wearability. Presented at: Proceedings of the 2017 ACM International Symposium on Wearable Computers; Sep 11-15, 2017. [CrossRef]
- Bergmann JHM, Chandaria V, McGregor A. Wearable and implantable sensors: the patient’s perspective. Sensors (Basel). Dec 5, 2012;12(12):16695-16709. [CrossRef] [Medline]
- Peek STM, Wouters EJM, van Hoof J, Luijkx KG, Boeije HR, Vrijhoef HJM. Factors influencing acceptance of technology for aging in place: a systematic review. Int J Med Inform. Apr 2014;83(4):235-248. [CrossRef] [Medline]
- Brown SA, Venkatesh V. Model of adoption of technology in households: a baseline model test and extension incorporating household life cycle1. MIS Q. Sep 1, 2005;29(3):399-426. [CrossRef]
- Moore K, O’Shea E, Kenny L, et al. Older adults’ experiences with using wearable devices: qualitative systematic review and meta-synthesis. JMIR Mhealth Uhealth. Jun 3, 2021;9(6):e23832. [CrossRef] [Medline]
- Puri A, Kim B, Nguyen O, Stolee P, Tung J, Lee J. User acceptance of wrist-worn activity trackers among community-dwelling older adults: mixed method study. JMIR Mhealth Uhealth. Nov 15, 2017;5(11):e173. [CrossRef] [Medline]
- Law M, Sutherland C, Ahn HS, et al. Developing assistive robots for people with mild cognitive impairment and mild dementia: a qualitative study with older adults and experts in aged care. BMJ Open. Sep 24, 2019;9(9):e031937. [CrossRef] [Medline]
- Mair FS, Montori VM, May CR. Digital transformation could increase the burden of treatment on patients. BMJ. Nov 25, 2021;375:n2909. [CrossRef] [Medline]
- Peterson CM, St Louis RM, Flannagan C. Enhancing enrollment and adherence in long-term wearable research on dementia: qualitative systematic review and meta-synthesis. JMIR Aging. Jul 31, 2025;8:e63768. [CrossRef] [Medline]
- Ehn M, Eriksson LC, Åkerberg N, Johansson AC. Activity monitors as support for older persons’ physical activity in daily life: qualitative study of the users’ experiences. JMIR Mhealth Uhealth. Feb 1, 2018;6(2):e34. [CrossRef] [Medline]
- Wong AKC, Lee JHT, Zhao Y, Lu Q, Yang S, Hui VCC. Exploring older adults’ perspectives and acceptance of AI-driven health technologies: qualitative study. JMIR Aging. Feb 12, 2025;8:e66778. [CrossRef] [Medline]
Abbreviations
| BU-ADRC: Boston University-Alzheimer’s Disease Research Centre |
| COREQ: Consolidated Criteria for Reporting Qualitative Research |
| EDoN: Early Detection of Neurodegenerative Diseases |
| MCI: mild cognitive impairment |
| SRQR: Standards for Reporting Qualitative Research |
Edited by Alicia Stone; submitted 12.Sep.2025; peer-reviewed by Judith Scott, Lars Masanneck; final revised version received 13.Mar.2026; accepted 31.Mar.2026; published 29.May.2026.
Copyright© Sarah Wilson, Emily Beswick, Zachary Popp, Salman Rahman, Sharandeep Bhogal, Tim Whitfield, Spencer Low, Raiyan Khan, Clare Tolley, Zuzana Walker, Rhoda Au, Sarah P Slight. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 29.May.2026.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research (ISSN 1438-8871), is properly cited. The complete bibliographic information, a link to the original publication on https://www.jmir.org/, as well as this copyright and license information must be included.

